Objective: The purpose of this research was to verify the
effectiveness of an eight-week quadriceps strengthening
program on pain, function and quality of life of patients
with knee osteoarthritis. Methods: A hundred patients were
randomized into two groups: 1- Exercise Group (ExG) and
2- Orientation Group. The Timed Up and Go (TUG) test,
the Numerical Rating Scale (NRS) and the Short Form-36
were used for the assessment. Results: Eighty-one patients
completed the survey. According to the intention to treat (ITT)
analysis, there was statistically significant difference in ExG
compared to OG in all the variables assessed. Conclusion:
The program quadriceps strengthening exercises applied in
this randomized clinical trial was effective in improving pain,
function and quality of life of patients with knee osteo