Among such children, rates of invasive pneu- mococcal disease caused by nonvaccine sero- types fell by 31% from the baseline period to 2012 and the rates of disease due to PCV7 sero- types declined by 86%, most likely confirming that HIV-infected children were benefiting from PCV use. Reductions in PCV13-serotype disease
in 2009 and 2010, before the introduction of PCV13, are also most likely a result of ART.