. In addition, all of the isolated compounds
except akuammidine (8) were evaluated for their antibacterial
activities against S. aureus ATCC 25922, K. pneumoniae ATCC 13883,
E. faecalis ATCC 10541, E. coli ATCC 11775 and P. aeruginosa ATCC
27853. Compounds 1, 5 and 10 exhibited significant antibacterial activity
against E. faecalis, and 3, 9 and 14 against P. aeruginosa, respectively, with
MIC value of 0.781 μg/mL, while 14 showed moderate activity against
K. pneumonia with MIC value of 1.56 μg/mL (See Table 3).
. In addition, all of the isolated compoundsexcept akuammidine (8) were evaluated for their antibacterialactivities against S. aureus ATCC 25922, K. pneumoniae ATCC 13883,E. faecalis ATCC 10541, E. coli ATCC 11775 and P. aeruginosa ATCC27853. Compounds 1, 5 and 10 exhibited significant antibacterial activityagainst E. faecalis, and 3, 9 and 14 against P. aeruginosa, respectively, withMIC value of 0.781 μg/mL, while 14 showed moderate activity againstK. pneumonia with MIC value of 1.56 μg/mL (See Table 3).
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