Results. Of the 217 patients who were included in the study,
61.8% (N=134) had a history of at least 1 relapse. There was
no significant difference (p>0.05) between those who relapsed
and those who did not relapse in terms of gender, marital
status or employment status. Approximately 46% (N=61) of
those who relapsed had co-morbid psychiatric disorders,
compared with 10.8% (N=9) in those who did not relapse
(p<0.0001), but there was no significant difference between
the two groups when comparing the presence of co-morbid
medical disorder (p=0.348). Nearly half (N=63) of patients
who relapsed had a history of substance abuse (p=0.0054);
cannabis was significantly more abused (p=0.0014). Twothirds
(N=138) of the study population did not adhere to their
treatment, of whom 80.4% (N=107) experienced a relapse
(p<0.0001). Significant multiple logistic regression models for
patients who relapsed included poor adherence due to sideeffects
(odds ratio (OR)=3.032; p=0.023; 95% confidence
interval (CI) 1.168 - 7.870); poor adherence due to lack of
insight (OR=5.29; p<0.0001; 95% CI 2.28 - 12.20), and
co-morbid depressed mood (OR=5.33; p<0.001; 95% CI
2.32 - 12.22).
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