measured the thickness of stratum
corneum, epidermis and whole skin of humans and rats. While the
thickness of the stratum corneum was similar (rat, 18 μm; human,
17 μm), the epidermis (human, 47 μm; rat, 32 μm) andwhole skinwere
thicker for human (human, 3 mm; rat, 2 mm). Because the stratum
corneum is considered the predominant barrier to permeability