Other uses may include treatment of chronic neurodegenerative
conditions because curcumin has shown protective
abilities against neurotoxic and genotoxic agents. For
example, in the case of Alzheimer’s disease, curcumin has
shown disaggregation of amyloid-β peptide. Other activities
include inhibition of NFκB, prevention of fibril and oligomer
formation, inhibition of Egr-1, amyloid-β peptide cell death,
and activation of transcription factors