Changes in protein levels of both p75 and TROY have been previously reported
in postmortem hippocampal regions from schizophrenia sufferers
compared to controls in two independent brain cohorts (Stanley
consortium brain cohort [30] and the NewSouthWales Brain Bank Network
schizophrenia case–control cohort [31] respectively), supporting a
role of these two proteins in the pathophysiology of schizophrenia and
their potential as candidate genes in the susceptibility of schizophrenia