Despite the large number of publications concerning
the health benefits of b-carotene, Davison et al. (1993)
pointed out that the characteristics that make a given
carotenoid effective and the relative efficacy of the
individual carotenoids are not known.
Moreover, dose
response and pharmacokinetics relationships remain
unexplored.
This needs to be done because of the
possible negative effect of b-carotene such as the
potential hemorrhagic toxicity of a large dose of bcarotene