Lignin represents between 26 to 29% of lignocellulose, and is strongly bounded to cellulose and hemicellulose, hiding them and protecting them from the hydrolase attack. Lignin peroxidase is the major enzyme involved in lignin degradation. Phanerochaete chrysosporium is the most recognised fungi for lignin degradation.
So, lignocellulose hydrolysis is a very complex process. Effective cellulose hydrolysis requires the synergetic action of several cellulases, hemicellulases and lignin peroxidases.
Despite this, lignocellulose is a very abundant and cheap natural renewable material, so a lot of work has been conducted on its microbial breakdown, specially with fungal species.