In this study, we detected nine different types of fatty acids in
10L of human serum using conventional GC–MS after derivatization
to methyl esters using PTSA as an acid catalyst. Among the
identified fatty acids, GLA and DGLA concentrations were significantly
lower in women than in men. This difference may be due to
differences in the biosynthetic production and/or metabolic processes
of fatty acids in men and women.
In future studies, we will further investigate the differences in
serum concentrations of fatty acids between healthy subjects and
patients with neurological disorders, such as schizophrenia.