HCFC-141b is manufactured in closed-systems, thus significant exposures to workers is unlikely. However, exposure can come from off-gassing during foam manufacturing or after the foam is produced or from non-self-contained solvent systems. Proper ventilation, especially in low places where heavy vapors might collect, is required to reduce potential exposure to workers. Always refer to the (Material) Safety Data Sheet ((M)SDS) for guidance on the appropriate personal protective equipment to be used and on the safe handling of this material.