NF- κB is a ubiquitous and well-characterized transcription factor
controlling the expression of genes encoding the pro-inflammatory
cytokines, chemokines, adhesion molecules, inducible enzymes
(NOS2 and COX-2) etc. [43]. In the present study, the protein levels
of NF- κB p65 subunit in nucleus of adipocytes were compared, and
cocoa supplemented exhibited significant lower levels of nuclear p65
levels than that of HF-fed controls.