stimulation of neoangiogenesis, acceleration in decontamination
of the tissue wounds, elimination of the local interstitial edema,
enhancing the local blood circulation, deformation of the wound
bed, stimulation of proliferation, reduction in area and volume of
the wound defect, enhancing the tissue oxygenation, prophylaxis
of nosocomial wound infections, enhancing local effect of the
general drug treatment, and reducing the cost and treatment
duration.
Organ-sparing tactics: We follow the organ-sparing principle of
surgical tactics in stages 2–4 of the diabetic foot syndrome. We
perform a corrective mini-osteotomy in neuropathic ulcers, stage