The formation of the.Endocytic clathrin-coated vesicles occurs through the interaction.Of clathrin heterotetrameric adaptor, protein - 2 (AP-2), and several accessory proteins such as Epsin Eps15 AP180 / CALM,,, And dynamin.Clathrin in which, the light chain and heavy chain form a unique structure.Called the clathrin triskelion as well, as AP-2 are recruited by epsin.To the plasmamembrane in response to receptor-mediated internalization.Signals.
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