7. Conclusion
Heterocyclic amines are potent mutagens that are formed in
cooked meat products. Their formation is highly dependent on
various factors such as cooking method, cooking time, cooking
temperature, type of meat, fat contents, moisture contents, pH and
creatinine contents of meat. Many studies conclude that these
HAAs are responsible for causing cancers in humans and animals.
HAAs can be detected by using modern techniques like GC, LC,
HPLC and MS. Still further research is needed to discover more
rapid techniques by which these can be identified more effectively.
The potential of some other rapid techniques like spectroscopies
and some biophysical methods should also be evaluated in the
future for quantification of HAAs.
HAAs concentration can be decreased by reducing cooking time
and temperature, by using various natural and synthetic antioxidant
substances and by giving pretreatments like dipping in marinades
and microwave application. So, more research is required to