In ordertounderstandthemechanismsofanti-Helicobacter
pylori activity, proteinsynthesisinhibition,DNAgyraseinhibition,
dihydrofolate reductaseinhibitionand Helicobacter pylori antiadhesion
assayswerecarriedout.Proteinsynthesisinhibitorsviz.,
clarithromycin andtetracycline,havebeensuccessfullyusedin
the eradicationof Helicobacter pylori in human(