Tumor differentiation — no./total no. (%) 0.85
Well or moderately differentiated 880/958 (92) 422/461 (92) 311/337 (92) 85/94 (90) 62/66 (94)
Poorly differentiated 78/958 (8) 39/461 (8) 26/337 (8) 9/94 (10) 4/66 (6)
Microsatellite instability — no./total no. (%) 0.84
None or low level 800/952 (84) 382/460 (83) 283/332 (85) 81/95 (85) 54/65 (83)
High level 152/952 (16) 78/460 (17) 49/332 (15) 14/95 (15) 11/65 (17)
CIMP — no./total no. (%) 0.84
Low or negative 755/916 (82) 366/438 (84) 264/323 (82) 75/93 (81) 50/62 (81)
High 161/916 (18) 72/438 (16) 59/323 (18) 18/93 (19) 12/62 (19)
BRAF — no./total no. (%) 0.94
Wild-type 828/959 (86) 400/464 (86) 288/335 (86) 84/95 (88) 56/65 (86)
Mutant 131/959 (14) 64/464 (14) 47/335 (14) 11/95 (12) 9/65 (14)
KRAS — no./total no. (%)