2.2. Clinical Samples. A total of 101 primary gastric cancer
tissues were obtained at the 1st Affiliated Hospital of Sun
Yat-senUniversity,Guangzhou, China, between January 2006
and June 2006. Patients who underwent radical gastrectomy
were included, while patients who received neoadjuvant
chemotherapy or chemoradiotherapy were excluded
from the study. Clinicopathological parameters evaluated
included age, gender, tumour location, tumour size, gross
tumour type, tumour histological type, depth of invasion,
lymph node involvement, distant metastasis, and TNM stage.
Tumour gross types were classified as either infiltrating or
noninfiltrating. Tumour histological types were classified as
either well differentiated (well and moderately differentiated
adenocarcinomas) or undifferentiated (poorly differentiated
adenocarcinomas, signet ring cell carcinomas, andmucinous
adenocarcinomas). Depth of tumour invasion, lymph node
involvement, and distant metastasis were assessed according
to the 7th edition of Union for International Cancer Control/
American Joint Committee on Cancer (UICC/AJCC)
guidelines. The potential radical resection gastric cancer
patients received gastrectomy and D2 lymphadenectomy.The
patients received postoperative chemotherapy using epirubicin,
cisplatin, and 5-fluorouracil regimen as indicated by the
concurrent UICC/AJCC guidelines. In addition, 20 human
adjacent normal gastric tissues were obtained. Chronic
atrophic gastritis, ulcer, and erosion were not detectedmicroscopically
in the adjacent gastric tissue samples.
2.2. Clinical Samples. A total of 101 primary gastric cancertissues were obtained at the 1st Affiliated Hospital of SunYat-senUniversity,Guangzhou, China, between January 2006and June 2006. Patients who underwent radical gastrectomywere included, while patients who received neoadjuvantchemotherapy or chemoradiotherapy were excludedfrom the study. Clinicopathological parameters evaluatedincluded age, gender, tumour location, tumour size, grosstumour type, tumour histological type, depth of invasion,lymph node involvement, distant metastasis, and TNM stage.Tumour gross types were classified as either infiltrating ornoninfiltrating. Tumour histological types were classified aseither well differentiated (well and moderately differentiatedadenocarcinomas) or undifferentiated (poorly differentiatedadenocarcinomas, signet ring cell carcinomas, andmucinousadenocarcinomas). Depth of tumour invasion, lymph nodeinvolvement, and distant metastasis were assessed accordingto the 7th edition of Union for International Cancer Control/American Joint Committee on Cancer (UICC/AJCC)guidelines. The potential radical resection gastric cancerpatients received gastrectomy and D2 lymphadenectomy.Thepatients received postoperative chemotherapy using epirubicin,cisplatin, and 5-fluorouracil regimen as indicated by theconcurrent UICC/AJCC guidelines. In addition, 20 humanadjacent normal gastric tissues were obtained. Chronicatrophic กระเพาะอาหาร แผล และการกัดเซาะไม่ได้ detectedmicroscopicallyในตัวอย่างเนื้อเยื่อในกระเพาะอาหารที่อยู่ติดกัน
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