Prior treatment, affected teeth, region as well as the respective indication were documented. The dentist made a decision concerning sedation and dose of the local analgesic. For each patient, a region of B3 adjacent teeth was examined. If there were more than one area to be treated, the region that was treated first was documented. For each patient, the duration of the treatment as well as the achieved analgesia (complete, sufficient, insufficient, none) after a period of 5–7 min was noted. If the analgesia was rated ‘‘insufficient’’ or ‘‘none’’, a second injection was administered and documented. The patient assessed the efficacy subjectively. In addition, the injection technique as well as dosage of the local analgesic (primary and sec- ondary injection as well as total dose) were documented. If sedation was needed, the character of the sedation as well as the special drug and its concentration were recorded. The dentist rated the quality of local analgesia after the treatment as ‘‘complete’’, ‘‘sufficient’’, ‘‘insufficient’’ and ‘‘no rating possible’’. If ‘‘insufficient’’ or ‘‘no rating pos- sible’’, failed analgesia was documented. One day after treatment, a structured telephone interview with the patient or the parents was conducted to examine the duration of subjective soft tissue analgesia—recorded in minutes by the patients and/or legal guardians while touching the tissues—as well as potential side-effects. The patients remained on a follow-up schedule for 14 days after treatment.