Mechanistically RUNX1 represses Elf5, a master regulatory TF gene for alveolar cells, and regulates mature luminal TF/co-factor genes (e.g., Foxa1 and Cited1) involved in the ER program.
Mechanistically RUNX1represses Elf5, a master regulatory TF gene for alveolar cells, and regulates mature luminalTF/co-factor genes (e.g., Foxa1 and Cited1) involved in the ER program.