In conclusion, low- vs. high-sodium diet in Caucasianswith normal BP decreases BP <1%. A significant concomitantand persistent increase in plasma renin, plasma aldosteroneand to a lesser degree of plasma adrenaline and plasmanoradrenaline may contribute to the small effect of sodiumreduction on BP. Furthermore, sodium reduction resultedin a significant increase in plasma cholesterol (2.5%) andplasma triglyceride (7%), which expressed in percentage,was numerically larger than the decrease in BP. The increasein triglyceride was numerically unchanged in studies witha duration of at least 2 weeks and in studies with sodiumreduction to moderate levels of sodium intake. Due to therelatively small effects and due to the antagonistic nature ofthe effects (decrease in BP, increase in hormones and lipids),these results do not support that sodium reduction mayhave net beneficial effects in a population of Caucasians. InCaucasians with elevated BP, short-term sodium reductiondecreases BP by ~2–2.5%, indicating that sodium reductionmay be used as a supplementary treatment for hypertension.In Asians and blacks, the effect of sodium reduction wasgreater, but at present too few studies have been carried outto conclude different from that above.Acknowledgments: Jacob Riis, Rasmus Moustgaard, and Dr Peter Gøtzsche,
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