In this article DNA was successfully immobilized onto nanocellulose membranes using UV-irradiation. The DNA-immobilized
nanocellulose samples efficiently bound anti-ds-DNA IgG in vitro.
Albeit some residual non-specific IgG binding was observed in the
samples, the IgG removal was mainly due to specific interactions
between ligand and ligate. The capacity of the IgG binding could
be directly controlled by varying the amount of DNA bound onto
nanocellulose. The described material is an interesting candidate
for development of medical apheresis materials in SLE treatment.