Another hormone that is crucial in obesity is Leptin.
This hormone is produced by the fat cells and is supposed to send signals to the hypothalamus (the part of our brain that controls food intake) that we’re full and need to stop eating.
Obese people have lots of fat and lots of leptin. The problem is that the leptin isn’t working as it should, because for some reason the brain becomes resistant to it (7).
This is called leptin resistance and is believed to be a leading factor in the pathogenesis of obesity.