In this presentation a simple liquid chromatographic
method has been described for the simultaneous determination
of saccharin, paracetamol, phenacetin andmethaqualone in an illicit methaqualone samples. To
demonstrate the usefulness of this method samples were
also analyzed by employing Clarke’s HPLC methods
(Anthony et al. 2003) for determination of paracetamol,
phenacetin and methaqualone where as Tibbels and
Smith method (Tibbels & Smith 1988) was used for
analysis of saccharin.