Dried rhizomes of C. domestica were ground into powder. The turmeric powder was extracted with ethanol and then evaporated at low pressure to obtain ethanol extract in the form of a semisolid containing oleoresin and curcuminoids. The oleoresin was removed to yield curcuminoids extract (total curcuminoids content between 75% and 85%). The peak ratio of curcumin to demethoxycurcumin and bisde¬methoxycurcumin in the extract was determined by high-performance thin-layer chromatography. The peak ratio of curcumin to demethoxycurcumin to bisdemethoxycur¬cumin was 1:0.59:0.23. The extract (calculated for 250 mg of curcuminoids) was filled into a capsule under Good Manufacturing Practices standards.