The adverse effects of increasing n-6 LA from 6% of food energy to 15% in this cohort are not necessarily generalizable to lower LA intakes; therefore, some caution should be used when extrapolating resultsto other populations. Finally, because
the SDHS investigated secondary prevention of coronary heart disease in men aged 30-59 years, results are not necessarily
generalizable to women, men aged younger than 30 years or older than 59 years, or populations without established coronary heart disease.