In support of this, re-analysis of data generated from a prior methods study of 100 participants with both baseline serum and heparin plasma samples found poorer correlations and agreement across categories between plasma and serum levels specifically for the 13 platelet-derived inflammatory factors compared to the other non-platelet inflammatory factors evaluated (data not shown) (40). Additionally, while our study included almost 80 different markers of inflammation, we cannot exclude the possibility that aspirin is associated with additional inflammatory markers not included within our panels