Anal Atresia
Some children with VACTERL association may have a condition in which a thin covering blocks the anal opening or the passage that normally connects the anus and the lowest part of the large intestine (rectum) fails to develop, a condition is known as anal atresia or imperforate anus. This condition prevents the normal passage of bowel contents. Some studies suggest that the involvement of the rectum/anus relates to a major risk for genital anomalies, which are usually more serious in boys