NICE (2008) suggests that patients’skin should be prepared for surgery using an antiseptic that is an aqueous or alcohol-based preparation such as povidone-iodine or chlorhexidine. Howerver, the DH (2007) High Impact Intervention care bundle recommends 2% chlorhexidine gluconate and 70% isopropyl alcohol solution, and one study has shown that 2% chlorhexidine gluconate and 70% isopropyl alcohol solution is more effective in reducing microbial load (Hibbard 2005). If the patient has sensitivity to this solution, then povidone-iodine application should be used. Complete time out activity