As EPP causes the release of
many inflammatory mediators such as kinin, serotonin and
prostaglandins, it might be possible that these extracts also affect
the release and/or synthesis of these mediators. The most potent
inhibition of both extracts at all concentrations was observed at
15 min suggesting that both extracts strongly inhibit the release
and/or the effect of histamine and serotonin which are the first
released inflammatory mediators of inflammation