The finding that AMPs can inhibit intracellular pathways suggest that there might be mechanisms of cellular uptake of AMPs. Two such mechanisms have been reported: direct penetration and endocystosis. According to Jones , cellular uptake of AMPs can take place through endocytosis, which includes macropinocytosis and receptor mediated endoeytosis. In macropinocytosis, the cell membrane folds inward and forms vesicles with the help of dynamin proteins. These vesicles are called macropinosomes and they are like small cells with only a membrane around them. In receptor mediated endocytosis, a part of the membrane is coated with clathrin or caveolin proteins followed by pit formation. Later, these pits bud from the membrane to inner side of the cell and form vesicles.