primaquine induced RBC membrane damage was significantly correlated with concentration of primaquine. Height, Ra and Rq of the normal RBCs were treated with primaquine and vitamin C which showed about 50% reductions compraed to those that were only treated with primaquine. On the other hand, height,Ra and Rq of the G6PD deficient RBCs were treated with primaquine and vitamin C, which are following the opposite trend. Finally diameter values of normal RBCs were treated with primaquin and vitamin C, which are increased about 20% compared to those only treated with primaquin.