Astaxanthin (3,3′-dihydroxy-β-carotene-4,4′-dione), which is one of the most powerful antioxidants among carotenoids, is extensively used as a pigment source in aquaculture and also gained broad application in pharmaceutical and nutraceutical industries due to the strong antioxidant property [1]; astaxanthin possesses 500-fold and 38-fold stronger free radical antioxidant activity of vitamin E and β-carotene, respectively [2], [3] and [4]. Haematococcus pluvialis accumulates high levels of the red ketocarotenoid pigment, natural astaxanthin up to 4% of its dry mass [5]. The market price of natural astaxanthin from H. pluvialis is approximately $7000 per kg because it is preferred for human consumption