Pre-eclampsia is not a new disease. It has almost the
same prevalence all over the world. This fact suggests
that we are dealing with a disease that is not easily
amended by external environmental factors. Preeclampsia
is perhaps a consequence of the relentless
conflict of interest between the mother and the fetus
[29]. The placenta is mainly of fetal origin. Paternally
derived genes in fetal cells will provoke maternal
responses. The interest of the fetus is to grow as large
and mature as possible before birth in order to increase
the chance of extra-uterine survival. There is a limit to maternal adaptation to this demand, if the mother is to
retain her own good health.