To test and implement pre-selected separation techniques to recover butanediol (BDO) and itaconic acid (IA)
from fermentation broth at a scale up to 50 L.
• To apply BDO and IA recovery technique as ISPR to improve productivities and feedstock impurities inhibition
• To test and implement techniques to purify BDO and IA from the stream coming out of the separation step at a
scale up to 50 L.
• To deliver purified samples of IA and BDO for application research in WP5 (kg scale• To provide information for integration of fermentation and downstream sections to produce BDO and IA;
• To test engineering concepts from WP2 and WP3 via pilot-scale to industrial scale;
• To demonstrate the technical feasibility of the production of platform chemicals on pilot-scale by efficient
processes with optimized continuous fermentation and novel integrated production and separation techniques.