The present study was designed to evaluate the current practice of Laptop computer and computer related health problems among college students, based on ergonomics. Material and Methods: The cross-sectional study was conducted over a three month timeframe, from April to June, 2013 in tertiary care hospital and teaching medical college. We included 100 students with age group 22-28 years, using laptop computer. Pre-designed and content validated, self-reporting questionnaire was used for data collection. Student’s refusal for participation and incomplete questionnaire were excluded in the study. Results: Current practice of laptop’s usage was ergonomically improper. Prolonged usage in improper posture has created various musculoskeletal problems among medical students.