Therapeutic and maximum tolerated doses were determined by the degree of erythema present.
Modern equipment and sophisticated treatment planning techniques produce a “skin-sparing” effect, with the therapeutic dose delivered to the target organ, minimizing the dose to the skin. Still, approximately 95% of patients receiving radiation therapy may experience some degree of skin reaction, ranging from mild erythema to more serious and uncomfortable moist desquamation.5 Severe moist desquamation results in pain and discomfort, and may require a break in treatment, pos- sibly compromising the effectiveness of treatment