Background/Aims: Early intervention with nutritional
supplementation has been shown to halt malnutrition
and may improve outcome in some patients
with colorectal cancer. The aim of this study was to
investigate whether dietary counseling, oral nutrition
and megestrol acetate during chemotherapy
affected nutritional status and survival in patients
with advanced disease. Methodology: Six hundred
and twenty-eight patients with colorectal cancer advanced
disease were included in the study from January
2000 through December 2009 and divided into
one of two groups. Group I consisted of 315 patients
who were monitored prospectively and were given
nutritional support. Group II included 313 patients
without nutritional counseling and support. After
the completion of chemotherapy all patients were
evaluated (BMI, NST, Appetite Loss Scale and ECOG).
Results: After the completion of chemotherapy, there
were lower proportions of patients in Group I with a
BMI