In this paper, we have described our efforts to use OC to develop a new food material from
OC by fermentation with R. oligosporus and combination with banana. We have investigated
two activities, ROSA, and the effects of the new food material from OC on obese dogs. First,
in the ROSA studies, a synergistic effect on ROSA between OT and banana was observed,
and the activity of OTB was approximately 30-fold more potent than that of OC alone by
XYZ system. We concluded that ROSA of OTB was attributable to components contained in
the dietary fiber portion of the residue after extraction with 80% ethanol and water. This is
the first report about the synergistic effect of fermented OC and banana on ROSA by XYZ
system (Suruga et al., 2007). Secondary, OTBp showed a dietary effect on obesity in dogs.
This clinical study was a part of application researches of the OTB. In the veterinary clinical
study, OTBp reduced the body weight and BCS in the obese dogs in a time-dependent
manner during the study. Moreover, the ALP activity of the two dogs was lowered than that
of the control (0 day). This result indicated that OTBp could have improving effect on the
liver function because of the potent antioxidant activity present in OTB. From these results,
OTBp is thought to have an improving effect on liver function, and a diet effect on the body
weight without any adverse reactions. OTB prepared from OC by fermentation and
combination with banana could be developed as a useful, novel food material and/or
nutritional supplement with both antioxidant and dietary effects. Further research and
development is undergoing.