5. Conclusion
We report the fabrication of rotary jet spun biohybrid PCL/gelatin and PCL/collagen nanofibers that have an extremely high degree of alignment. We demonstrate that the physical, chemical and mechanical properties of these super-aligned nanofibers (SANF) are dependent on the percentage composition of protein in these fibers. PCL/collagen-75/25 SANF scaffolds were selected for cell culture study as that composition provided better mechanical and biodegradation properties compared to other hybrid or pure polymer compositions. Cell culture results demonstrated better cell attachment, proliferation and function on SANF hybrid fibers, suggesting their potential utility in tissue engineering applications.