Static fermentation is simple and does not need high technology but there are many disadvantages such as diffusion problem, difficulties in monitoring the fermentation condition and scale up. Scaling up of the production is laborious, tedious and uneconomical for commercialization. Many of the limitations in static cultures can be overcome in agitated culture by using Continuous Stirrer Tank Reactor (CSTR). The product from the agitated medium is not in pellicle form but rather is formed as reticulated cellulose slurry. This technique also comes with culture instability problems demonstrated by loss of the ability to make cellulose and the gradual overgrowth of cellulose producing cells by cellulose non producers (Cel-) types. Interestingly, in RDR, discs alternately soak the organisms in the medium and expose them to air providing better aeration compared to conventional method. Apart from that, the discs provide larger surface area for cellulose attachment to both sides of the discs hence give RDR many advantages which are higher production yield, less labour and ease for up scaling.