This study aimed at the selection of the suitable mango variety for mango wine. The study focused on two main factors: the maturative stage of mango (nearly ripe and ripe) and the varieties of mango (Khiew sawiay, Mahachanok, Nongsang and Sampee). The physico-chemical composition of raw material and mango wine were determined. The experimental design was 2 x 4 Factorial in CRD. It was found that ripe mango contained 17.22 deg Brix of the highest total soluble solids whereas the lowest total of acidity was 0.55 percent. The quality of ripe stage was more suitable for using as raw material for wine making than nearly ripe one. The total acidity increased from 0.50 percent to 70 percent during fermentation period which differed from varieties of 8 days of ripe Nongsang, and 11 days of nearly ripe Mahachanok and Sampee. The total acidity and volatile acidity of ripe Khiew sawiay were approached to the standard range of 0.630 percent and 0.054 percent after 90 days of age. The ripe Mahachanok wine trended preferable over all the other types. In addition, product after stopped fermenting provided good composition of 13.3 deg Brix, and 0.6 percent of total acidity.