Creatine (gr. kreas) was discovered in 1832 in beef meat by the French chemist
Michel Chevreul (Shao and Hathcock, 2006; Wyss and Kaddurah-Daouk, 2000).
Creatine (N-aminoiminomethyl-N-methylglycine) is a guanidino compound with
a structure similar to the amino acids with a molecular weight 131 ∙ 103 Da and
a positive charge at physiological pH (Andres et al., 2008; Orsenigo et al., 2005).