In regimens employing methotrexate, woman typically are seen at least 24 hours after misoprostol administration, and approximately 7 day after methotrexate administration, at which time an ultrasound examination is performed. If the pregnancy persists, another dose of misoprostol is given, and the woman is seen again in 1 week of fetal cardiac activity is present, or in 4 weeks is no fetal cardiac activity. If' by the second visit, abortion has occurred, it usually is completed by suction curettage.