Once the patient has been stabilized, long-term issues, such as vocational rehabilitation, can be addressed. Medication dosage can be slowly reduced to a maintenance level. In particular, since depot medications tend to accumulate in muscle tissue over time, the dose should be gradually decreased in order to maintain a constant blood level. Attention must be paid to weight gain, possible diabetes, and elevated serum lipids. These are particular concerns for the newer generation of anti-psychotics. Body mass index (BMI) should be continuously monitored throughout treatment. Every individual being prescribed antipsychotic medication for more than a year should be checked for diabetes with either a fasting blood sugar or HbA1c. In additional Individuals with existing diabetes should have annual blood testing that includes HbA1c and serum lipid levels. Individuals with cardiovascular disease should have annual testing for serum lipid levels.