Numerous dental and skeletal abnormalities such as hypodontia, supernumerary teeth, abnormality in tooth size and shape, discrepancy in skeletal base relationships and malalignment of teeth are encountered in patients with cleft lip and palate. To develop the arches and to align the teeth, several phases of orthodontic treatment are in almost all cases unavoidable. Fixed orthodontic appliances facilitate the colonization of cariogenic mutans streptococci (MS), hence providing a negative impact on caries susceptible patients with cleft lip and palate when they undertake orthodontic treatment [2, 3]. Mutans streptococci have been associated in particular with early demineralization [3, 4].