In this paper, an anti-fouling composite coating was fabricated by blending zinc-graphite alloy powders with epoxy-silicone resin and characterized by EDS, SEM, XRD and ion titration. Compared with stainless steel and epoxy-silicone resin coating, the composite coating significantly inhibited the deposition of CaCO3 fouling. Only a small amount of fouling was observed on the surface of composite coating after it was immersed in CaCl2/NaHCO3 solution. The galvanic corrosion of zinc-graphite powders could release Zn2+ ions, which can reduce partially the nucleation and crystal growth rate of CaCO3 on the surface of composite coating. It was found that the morphologies of CaCO3 fouling changed from calcite to aragonite as the existence of composite coating. Meanwhile, CaCO3 fouling was prone to precipitate in bulk solution rather than on the surface of composite coating.