The invention provides a method for treating post-angioplasty or in-stent restenosis in an individual in need of such treatment, comprising administering to the individual an ED of morelloflavone. The invention also provides a method for treating post-angioplasty or in-stent restenosis in an individual in need of such treatment, comprising administering to the individual an ED of morelloflavone and an HMG-CoA reductase inhibitor