3. Results
3.1. Correlation between gene expression and compositional features
Besides analyzing the correlation between tumor suppressor gene expression level and their compositional features in 25 tissues, 6475 correlations were obtained, in which 117 are with p-value b 0.01 (Supplementary Table 1). The most significant features that have the lowest p-value for each tissue are listed in Table 1 and presented in Fig. 1.It should be pointed out that the adopted threshold for a significant level (p b 0.01) is not extremely low. Therefore, approximately 64 (1% of the total number 6475) features may be significant by chance that probably lead to some artifacts of the present results. Nevertheless, the majority of these significant features are informative.