Apart from the ability of obtaining knowledge and applying knowledge, entrepreneurs of business and management should be equipped with the ability of entrepreneurship, innovation and building wealth. Establishing a business is a career that needs to be fully engaged in. During the process there is no one who assists the entrepreneurs to make plans, decisions. When they are in trouble and crisis, they have to fight positively and down to earth so as to succeed. Career-orientated, the entrepreneurs are motivated by social recognition and they regard the realization of value as they aims. However, innovation is the inherent requirement of business management. In the era of knowledge economics, knowledge and technology make a growing contribution to the growth of economy. The transformation from technology to product takes less and less time. The inherent drive of technological and product innovation will make the economy a constantly innovative economy and the management of future society will be constant innovative management. One will be out of the game if he/she is not innovative. As for the manager of business, they must pay particular attention to “management system innovation”. The key is to arouse people’s initiative and innovation. Hence make them concerted with the enterprise’s operation and development. Building wealth is the foundation of establishing a business. The process of transform from building wealth into innovative enterprise needs many abilities. The famous entrepreneurial manager defines establishing a business as the combination of three factors “opportunity, resource and team”. An excellent entrepreneur may not have sophisticated knowledge, but ought to have such qualities: strong innovative spirit and entrepreneurial awareness. He never sticks to convention and follow the herd; he has strong wish to pursue achievement and is filled with spirit of adventure, denotation and endurance; he is very sensitive of the opportunities and can make high level decision; he is excellent in discovering opportunities and master it; he is highly responsible and confident and dares to fight in difficulty and rise from low ebb.